4-hydroxy-3-methoxy-4-methyl phenyl methanone

4-hydroxy-3-methoxy-4-methyl phenyl methanone - Names and Identifiers

Name	3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE
Synonyms	4-Hydroxy-3-Methoxy-4-Methylbenzophenone 4-hydroxy-3-methoxy-4-methyl phenyl methanone (4-hydroxy-3-methoxyphenyl)(p-tolyl)methanone (4-hydroxy-3-methoxy-phenyl)-(p-tolyl)methanone 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE 1-(4-hydroxy-3-methoxyphenyl)-3-p-tolylpropan-2-one (4-Hydroxy-3-Methoxyphenyl)(4-Methylphenyl)-Methanone Methanone, (4-hydroxy-3-methoxyphenyl)(4-methylphenyl)- 1-(4-Hydroxy-3-methoxyphenyl)-3-(4-methylphenyl)propan-2-one
CAS	134612-39-8
InChI	InChI=1/C15H14O3/c1-10-3-5-11(6-4-10)15(17)12-7-8-13(16)14(9-12)18-2/h3-9,16H,1-2H3

4-hydroxy-3-methoxy-4-methyl phenyl methanone - Physico-chemical Properties

Molecular Formula	C15H14O3
Molar Mass	242.27
Density	1.175g/cm³
Melting Point	103–105°C
Boling Point	432.066°C at 760 mmHg
Flash Point	164.331°C
Solubility	Dichloromethane
Vapor Presure	0mmHg at 25°C
Appearance	Solid
Color	Light Brown
Storage Condition	2-8°C
Refractive Index	1.588

4-hydroxy-3-methoxy-4-methyl phenyl methanone - Introduction

1-(4-hydroxy-3-methoxyphenyl)-3-(4-methylphenyl) propan-2-one, chemical formula C19H18O3, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
1-(4-Hydroxy-3-methoxyphenyl)-3-(4-methylphenyl) propan-2-one is a crystalline solid that forms a crystalline structure stabilized by hydrogen bonding interactions. It is soluble in common solvents such as ethanol, acetone and dimethyl ketone, and insoluble in water. Its melting point and boiling point are 180-182°C and 431.5°C, respectively.

Use:
1-(4-hydroxy-3-methoxyphenyl)-3-(4-methylphenyl) propan-2-one has a wide range of applications in organic synthesis. It can be used as a pharmaceutical intermediate for the synthesis of drugs and bioactive molecules. In addition, it is also used in the fields of dyes, fragrances and cosmetics.

Preparation Method:
The synthesis of 1-(4-hydroxy-3-methoxyphenyl)-3-(4-methylphenyl) propan-2-one can be achieved by a variety of methods. A common method is to react 3-(4-methylphenyl) acetone and p-methoxybenzaldehyde under basic conditions to produce the desired product. The specific reaction conditions can be determined according to the specific synthesis scheme.

Safety Information:
1-(4-Hydroxy-3-methoxyphenyl)-3-(4-methylphenyl) propan-2-one is generally safe under reasonable use. However, like all chemicals, it still needs to be handled with caution. During operation, care should be taken to avoid contact with skin, eyes and respiratory tract. Wear appropriate personal protective equipment such as protective gloves, glasses and masks during use. In addition, it needs to be stored in a cool, dry and well-ventilated place, and away from flammable materials and oxidants. In case of inadvertent contact or inhalation, rinse immediately with water and seek medical attention.

Last Update：2024-04-09 20:52:54